The Greco Mafia family is a historic and one of the most influential Mafia clans in Sicily, going back to the late 19th century. The extended family ruled both in Ciaculli and Croceverde Giardini, two south-eastern outskirts of Palermo in the citrus growing area. Members of the family were important figures in the Sicilian Cosa Nostra. Salvatore Greco "Ciaschiteddu" was the first ‘secretary’ of the Sicilian Mafia Commission, while Michele Greco, also known as The Pope, was one of his successors.
According to the pentito Antonio Calderone “the Greco’s effectively exercised power in the whole of Sicily.” According to Giovanni Brusca the Greco family was very important and the ones who tipped the balance in every internal Mafia war.